Normal and fibrotic liver parenchyma respond differently to irreversible electroporation
نویسندگان
چکیده
منابع مشابه
An update on irreversible electroporation of liver tumours.
OBJECTIVE. To investigate the clinical efficacy and safety of irreversible electroporation for ablation of liver tumour in humans. DATA SOURCES. The PubMed and MEDLINE databases were systematically searched. STUDY SELECTION. Clinical research published in English in the last 10 years until October 2013 that address clinical issues related to irreversible electroporation of human liver tumours w...
متن کاملRat liver regeneration following ablation with irreversible electroporation.
During the past decade, irreversible electroporation (IRE) ablation has emerged as a promising tool for the treatment of multiple diseases including hepatic cancer. However, the mechanisms behind the tissue regeneration following IRE ablation have not been investigated. Our results indicate that IRE treatment immediately kills the cells at the treatment site preserving the extracellular archite...
متن کاملTumor Ablation with Irreversible Electroporation
We report the first successful use of irreversible electroporation for the minimally invasive treatment of aggressive cutaneous tumors implanted in mice. Irreversible electroporation is a newly developed non-thermal tissue ablation technique in which certain short duration electrical fields are used to permanently permeabilize the cell membrane, presumably through the formation of nanoscale def...
متن کاملTemperature considerations during irreversible electroporation
a School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA 24061, USA Department of Bioengineering, Department of Mechanical Engineering and Graduate Program in Biophysics, University of California at Berkeley, Berkeley, CA 94720, USA Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew Un...
متن کاملIrreversible electroporation of the liver: is there a safe limit to the ablation volume?
Irreversible electroporation is a fast-growing liver ablation technique. Although safety has been well documented in small ablations, our aim is to assess its safety and feasibility when a large portion of liver is ablated. Eighty-seven mice were subjected to high voltage pulses directly delivered across parallel plate electrodes comprising around 40% of mouse liver. One group consisted in 55 a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: HPB
سال: 2019
ISSN: 1365-182X
DOI: 10.1016/j.hpb.2019.01.019